postoperative nausea and vomiting
Conditions
Interventions
Group LA:Before endotracheal intubation, use Lidocaine spray to carry out surface anesthesia on the throat
Group control:no operation before endotracheal intubation
Sponsors
The Second Affiliated Hospital of Xi'an Jiaotong University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Sign an informed consent form; 2. ASA classification: I-II level; 3. Age 18-65 years old; 4. Patients planned to undergo Elective surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: 1. Have a history of alcohol abuse and drug dependence (smokers do not contain nicotine); 2. Have neurological or mental disorders; 3. Have a history of brain dysfunction or brain injury; 4. There is Chronic pain and accompanying analgesic treatment; 5. There is extensive mucosal damage and ulceration in the mouth and throat; 6. BMI>28kg/m2 or<18kg/m2; 7. Diabetes is being treated with insulin or not; 8. Patients who have undergone chemotherapy before surgery and experience nausea and vomiting; 9. Patients who took known antiemetic drugs (Phenothiazine, Scopolamine, Corticosteroid and Tricyclic antidepressant) within one month before operation; 10. People who are allergic to the study Drug allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of postoperative nausea and vomiting; | — |
Secondary
| Measure | Time frame |
|---|---|
| the incidence of postoperative vomiting;the severity of postoperative nausea;the frequency of postoperative nausea;Numerical pain score, NRS;Remedial antiemetic medication;Remedial analgesics;Other adverse events; | — |
Countries
China
Contacts
Public ContactLyu Jianrui
The Second Affiliated Hospital of Xi'an Jiaotong University
Outcome results
None listed