Postoperative cognitive function
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.patients undergoing excision of pulmonary lesion; 2.age =50 years old; 3. ASA class II-III; 4. The patients signed the informed consent voluntarily.
Exclusion criteria
Exclusion criteria: Have central nervous system and mental illness; Obvious respiratory or circulatory system diseases, liver and kidney dysfunction before surgery; A history of alcohol or drug dependence; Inability to recognize words on cognitive function tests or severe hearing impairment; History of preoperative radiotherapy or chemotherapy or abnormal coagulation function; Long-term (more than six months) use of antipsychotics or sedatives or narcotic analgesics before surgery; The MMSE score is lower than the minimum score of the corresponding education level (primary school < 20, middle school (including technical secondary school) <22, university (including junior college) <24); Unable to communicate effectively with physicians verbally
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative cognitive function ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adiponectin;Hemodynamics;Inflammatory marks; | — |
Countries
China
Contacts
Hebei General Hospital