halitosis
Conditions
Interventions
Test:BOP mouthwashes containing antimicrobial peptides
control group:Remove the active ingredients of mouthwash
Sponsors
Hospital of Stomatology, Shandong University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: A) the body in good health; B) ranging in age from 18 to 70 years old; C) should first check the condition of teeth and gums, through inspection eligible to participate in this study; D) agreed to use mouthwash does not use any non test; E) without eating garlic, leeks, stinky tofu, easy to produce bad breath eating habits; F) to maintain good health habits, brush your teeth twice a day; G) by tone detector check, bad breath index (tone instrument is three times the average) p. 125; H) signed informed consent; I) 1 month before the start of the study does not use any antibiotic and antimicrobial agents.
Exclusion criteria
Exclusion criteria: A) at the same time to participate in other clinical research; B) the day use products containing phenols or mint flavor, such as the test with toothpaste, mouthwash, chewing gum, etc.; C) this product and its components have allergy history; D) AIDS, insulin dependent diabetes, cancer chemotherapy to within six months, immunodeficiency, autoimmune diseases or other serious illness; E) with severe gingivitis and periodontitis or oral ulcer, wearing parts or denture; F) to smoke or use tobacco products; G) nearly 1 week use antihistamines or nearly 1 months use immune inhibitors; H) is the subjects' security researchers believe that may affect the inspection procedures and complete the test of any disease and conditions; I) in pregnancy and lactation, women in menstrual period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The effective factors to cause the smelly component values;Improvement of subjective bad breath; | — |
Countries
China
Contacts
Public ContactMi Du
Hospital of Stomatology, Shandong University
Outcome results
None listed