head and neck cancer
Conditions
Interventions
CT-guided radioactive iodine-125 seed implantation:None
3D-printed template-assisted CT-guided radioactive iodine-125 seed implantation:None
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years; 2. The head and neck cancer have received external beam radiation therapy in the past; 3. Pathologically diagnosed with recurrent head and neck cancer; 4. Suitable for radioactive seed implantation needs; 5. No bleeding tendency, no serious or uncontrolled underlying diseases; 6. There are suitable puncture routes, and the expected therapeutic dose can be reached after implantation of radioactive seeds; 7. KPS >= 60, expected to be able to tolerate puncture/radioactive iodine-125 seed implantation, and the expected survival time greater than 3 months.
Exclusion criteria
Exclusion criteria: 1. Subjects with skin infection at the puncture site; 2. The lesion is close to the important organs or has a large range of liquefactive necrosis and the seed distribution is expected poor; 3. Subjects who are pregnant, lactating or mentally ill; 4. Poor compliance, unable to complete the treatment; 5. The researcher considers not suitable for participating in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety; | — |
Secondary
| Measure | Time frame |
|---|---|
| Objective response rate;Local control;Progress free survival;Overall survival;Dosimetric parameters; | — |
Countries
China
Contacts
Public ContactJunjie Wang
Peking University Third Hospital
Outcome results
None listed