irritable bowel syndrome
Conditions
Interventions
electro-acupuncture group with 2HZ:electroacupuncture treatment with a continuous wave of 2HZ
electro-acupuncture group with 2/100HZ:electroacupuncture treatment with a dilatational wave of 2/100HZ
sham electro-acupuncture group:non-acupoints sham electro-acupuncture treatment
Sponsors
School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: (1) Age between 20-40 years old (including 20 and 40 years old), right-handed, male or female (2) Meet the diagnostic criteria for the Rome IV diarrhea type irritable bowel syndrome subtype (3) Daily defecation diary for the past 2 weeks reported as Bristol fecal trait type 6 or 7 for at least 4 days and Bristol fecal trait type 1 or type 2 less than 4 days; The average daily abdominal pain (NRS) score for the past 1 week = 3 (4) Have not received acupuncture treatment in the past 6 months (5) Have not taken antidepressant drugs and drugs that have therapeutic effects on the symptoms of irritable bowel syndrome within 2 weeks before treatment, including traditional Chinese medicine or proprietary Chinese medicine, antidiarrheal agents, antispasmodic drugs, intestinal antibiotics, probiotic preparations, etc (6) No language and intellectual disability, can fill in the questionnaire normally (7) Voluntarily fill in the informed consent form
Exclusion criteria
Exclusion criteria: (1) Constipation IBS/mixed IBS, inflammatory bowel disease/microscopic colitis/celiac disease / organic bowel disease such as Crohn's disease (2) Diabetes, thyroid dysfunction (3) Severe acute/chronic organic diseases and kidney or liver disease (4) Previous abdominal surgery (patients with appendix surgery, hemorrhoidal surgery, polyp surgery for more than 3 months) (5) Pregnancy or lactation (6) History of alcohol and drug abuse (7) Are taking drugs that have an effect on the central nervous system (such as antiepileptic drugs, Antispasmodics, anxiolytics, sleeping pills), or patients with mental symptoms such as insomnia, anxiety, depression (8) Patients participating in other clinical trials, etc. (9) Contraindications to magnetic resonance examination: patients with pacemakers, neurostimulators, artificial heart valves, etc.; with aneurysm clips (except non-paramagnetic such as titanium alloys); Those with intraocular metal foreign bodies, inner ear implants, metal prostheses, metal prostheses, metal joints, ferromagnetic foreign bodies in the body; Patients with severe hyperthermia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The response rate at week 6;Pain Anxiety Symptoms Scale;Pain Catastrophizing Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| The response rate at other weeks;The IBS Symptom Severity Scale;The IBS Quality of Life;Te Patient Health Questionnaire-9;The Adequate Relief;abdominal pain;abdominal bloating;stool frequency;Fear of pain questionnaire;blinding and credibility evaluation;brain-spinal MRI; | — |
Countries
China
Contacts
Public ContactCun-Zhi Liu
School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine
Outcome results
None listed