Kidney disease
Conditions
Interventions
Non-actived group (cDC1?cDC2 non-actived):None
cDC1 dominant group (cDC1/cDC2>=1):None
cDC2 dominant group (cDC1/cDC2<1):None
Sponsors
Peking University Shenzhen Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1)18-80 years old; 2) Meet any of the following indications to take renal biopsy: (1) primary kidney diseases including nephritis syndrome and nephrotic syndrome (2) secondary kidney diseases (3) renal failure of unknown causes (4) patients who have asymptomatic microscopic hematuria or/and proteinuria, but have family history of kidney diseases (5) patients with renal transplantation exhibit proteinuria, hematuria, and/or renal dysfunction (6) patients who need repeated renal biopsy based on clinical evaluation. 3) Voluntarily sign an informed consent form. 4) Have clear contact information and contact person, and be able to complete regular follow-up.
Exclusion criteria
Exclusion criteria: 1) Renal biopsy cannot be performed due to any contraindications:(1) Obvious bleeding tendency (2) Mental disorders unable to cooperate with procedures (3) Solitary kidney (4) End stage pyelonephritis (5) Active infections including acute pyelonephritis and active renal tuberculosis (6) Renal tumors; 2) The number of glomeruli in renal tissue <5,unable to complete pathological diagnosis; 3) The follow-up time is less than 3 months; 4) Disagree to cooperate in completing follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| End stage renal disease;Kidney tranplatation;Death;More than 50% estimated glomerular filtration rate than baseline; | — |
Secondary
| Measure | Time frame |
|---|---|
| 24-hour urine protein; | — |
Countries
China
Contacts
Public ContactShuang Hou
Peking University Shenzhen Hospital
Outcome results
None listed