sedation and analgesia in patients with mechanical ventilation
Conditions
Interventions
Control group:All the patients received fentanyl in a dose of 0.5-2.0 µg/kg for analgesia induction and a dose of 0.3-1.07 µg/kg/h for continuous infusion. On this basis, the participants were treated
dexmedetomidine, maintained by continuous pumping at 0.2-0.7 µg/kg/h
and propofol, which was induced by intravenous infusion of 1.0-3.0 mg/kg within 5 min, and followed by continuous infusion of 0.5-4.0 mg/kg/h.
Treatment group:For the treatment group, auricular magnetic bead pressing was added as an adjuvant therapy on the basis of the control group
Sponsors
Xiyuan Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Patients admitted to ICU and EICU, aged = 18 years old, regardless of gender, with an estimated hospital stay of more than 24 hours; Patients who need to receive mechanical ventilation treatment during hospitalization due to their condition, with an estimated mechanical ventilation time of = 24 hours and need continuous analgesia and sedation; In order to ensure the stability of the baseline when patients with pain and restlessness are enrolled in the group, it is required that the CPOT score = 3 and SAS score = 5 when no sedative and analgesic drugs are given before hospitalization; The patient or family member has signed an informed consent form.
Exclusion criteria
Exclusion criteria: Those who are in a coma state before treatment and cannot undergo analgesic and sedative assessment; Infectious diseases, such as hepatitis B and active pulmonary tuberculosis; Researchers believe that there is poor compliance or inability to cooperate; Ear skin damage; Individuals who are allergic to adhesive tape.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CPOT score;SAS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adrenocorticotropic hormone;Cortisol;Melatonin;Methionine-enkephalin; | — |
Countries
China
Contacts
Public ContactLi Jie
Xiyuan Hospital, CACMS
Outcome results
None listed