Minimum effect concentration of adrenaline to offer a better view in functional endoscopic sinus surgery (FESS): a dose-finding study with biased-coin design (BCD) and double blindness.

Determining the minimum effect concentration of adrenaline to offer a better view in functional endoscopic sinus surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300073776

Enrollment

Unknown

Registered

2023-07-20

Start date

2023-08-01

Completion date

Unknown

Last updated

2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sinusitis, Polyp of nasal sinus, et al.

Interventions

grouping with dose level:Assign different dosages of the drug using BCD

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: ? FESS; ? Age 18-60 years; ? The ASA ?-?; ? Those who agree to participate in this study and sign an informed consent form.

Exclusion criteria

Exclusion criteria: ?ASA > II, ?Using drugs of cardiovascular system or the coagulation and fibrinolytic systems; ? Serious cardiovascular and cerebrovascular diseases; ? Chronic obstructive pulmonary disease, ? Chronic nephrosis and liver failure, ? Diabetes with serious complications; ? Severe anemia or malnutrition; ? Abnormal coagulation function; ? History of sinus surgery; ? Pregnant and lactating women.

Design outcomes

Primary

Measure	Time frame
Surgical Field Bleeding Score;Average Blood Loss;	—

Secondary

Measure	Time frame
Surgeon’s Satisfaction;	—

Countries

China

Contacts

Public ContactBing-Wei Hu

Tongde Hospital of Zhejiang Province

whoboy555@hotmail.com+86 134 5697 6077

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026