depression
Conditions
Interventions
Experimental Group One:Double target
Experimental Group Two:Single target
Control Group:Sham stimulation
Sponsors
The Second People's Hospital of Guizhou
Eligibility
Sex/Gender
All
Age
12 Years to 20 Years
Inclusion criteria
Inclusion criteria: Patient group: (1)12-20 years old, the Han nationality, right handed; (2) Diagnosed depression according to the ICD-10; (3) Have not received antidepressant treatment within one month, and have no history of electroconvulsive therapy or transcranial magnetic stimulation therapy. (4) HAMD-17 score >= 17; (5) No electronic or metal device implantation (pacemakers, defibrillators, steel plates, etc.) (6) Signed informed consent and be able to comply with the treatment plan. Healthy group: (1) Han Chinese, aged 12-20 years old, right-handed, with a primary school or above education level; (2) HAMD17 score<7 points; (3) HAMA14 score<7 points; (4) No electronic or metal device implantation (pacemaker, defibrillator, etc.).
Exclusion criteria
Exclusion criteria: Patient group: (1) Suffering from other mental disorders, such as mental retardation, schizophrenia, etc; (2) HAMD-17 score 8 points; (3) Suffering from organic brain diseases or severe physical diseases; (4) Have a history of Substance dependence; (5) There are contraindications for fMRI and fNIRS examinations in pregnant women;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fNIRS;fMRI;HAMD;Montgomery-Asperger Depression Rating Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| HAMA;Scale for Suicide Ideation, SSI;Positive and negative affect scale, PANAS;Connor davidson resilience scale, CD-RISC;Self-rating depression cale, SDS; | — |
Countries
China
Contacts
Public ContactShu Yanping
The Second People's Hospital of Guizhou Province
Outcome results
None listed