endocrine and metabolic diseases
Conditions
Interventions
Endocrine and metabolic disease group:none
Sponsors
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: ? Pregnant women ? Voluntary signing of informed consent.
Exclusion criteria
Exclusion criteria: ? Twin or multiple pregnancy; ? Severe pregnancy complications; ? Complicated with important heart, liver, kidney, blood system and autoimmune diseases before pregnancy; ? Associated with other diseases that may affect intestinal flora or metabolomics, including inflammatory bowel disease, irritable bowel syndrome, celiac disease, etc.; ? Gastrointestinal and biliary surgeries, including bariatric surgery and cholecystectomy; ? History of smoking, alcoholism, narcotic drug use; ? For women who keep stool samples; antibiotics within 2 months of specimen collection; probiotics within 1 week of specimen collection;take oral drugs that may affect intestinal flora.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pregestational/gestational diabetes mellitus;Thyroid dysfunction during pregnancy;Offspring metabolic disturbance; | — |
Countries
China
Contacts
Public ContactXinhua Xiao
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed