Type 2 diabetes
Conditions
Interventions
Control group:Health education
Morning moderate intensity exercise group:Moderate intensity aerobic exercise combined with resistance exercise
Evening moderate intensity exercise group:Moderate intensity aerobic exercise combined with resistance exercise
Sponsors
Shanghai University of Sport
Eligibility
Sex/Gender
All
Age
60 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Type 2 diabetes mellitus with mild cognitive impairment; 2. The main complaint was memory loss, the score of the Montreal Cognitive Assessment Scale was 24; 3. Blood glucose inclusion criteria according to the American Diabetes Association's classification of glucose metabolism status, blood glucose was well controlled and there were no serious chronic complications of diabetes; 4. Duration >= 3 years; 5. Aged 60-75 years; 6. BMI: > 23.9 kg/m^2 and weight fluctuation <= 3 kg in the past 3 months; 7. Sedentary and insufficiently physically active for the past three months.
Exclusion criteria
Exclusion criteria: 1. Have serious cardiovascular disease, other serious underlying disease or cancer; 2. Other factors that may cause cognitive impairment include cerebrovascular disease, craniocerebral trauma, various encephalitis, intracranial space occupation, metabolic encephalopathy, hypoxic encephalopathy, Parkinson's disease, thyroid and parathyroid diseases, etc.; 3. History of hypoglycemia; 4. Have depression or other mental illness or history, Hamilton Depression Scale >= 8 points; 5. Claustrophobia; 6. Irregular work and rest; 7. Have movement disorders or contraindications; 8. Smoking, drinking, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment (MoCA) socre; | — |
Secondary
| Measure | Time frame |
|---|---|
| Glucose;Hemoglobin;Triglyceride;Total cholesterol;High density lipoprotein cholesterol;Low density lipoprotein cholesterin;Insulin;c-peptide;Brain structure and function;Vascular endothelial function; | — |
Countries
China
Contacts
Public ContactJie Zhuang
Shanghai University of Sport
Outcome results
None listed