rosacea
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Healthy adult female aged 18-45; subjects who are willing to participate in the trial and are able to complete skin tests as required throughout the study; subjects who have read and signed the informed consent form before the study began; subjects who are healthy at the time of the test; subjects who can complete the prescribed content as required by the test plan; patients with mild to moderate rosacea should stop macrolides or retinoids for at least 6 weeks and related antibiotics, hormones, or calcineurin inhibitors for at least 4 weeks.
Exclusion criteria
Exclusion criteria: Pregnant and lactating women; patients with severe allergic diseases or who have been allergic to cosmetics in the last one to two years; subjects who enrolled in any other drug within three months before the trial began; Regular users of Chinese herbs, sleeping pills, sedatives, tranquilizers, or other addictive drugs; alcoholics, mental patients; or can not follow the doctor's advice to cooperate with the treatment; patients with cardiopulmonary insufficiency and serious underlying diseases; subjects who have other skin conditions that may interfere with the clinical evaluation of acne-like skin and/or put the subject at risk, or have a history of other severe skin conditions; subjects who the researchers believe are unable to participate for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Moisture content of skin stratum corneum;Skin water loss through epidermis TEWL;Microecological detection;LL-37 detection;Substance P detection; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse event; | — |
Countries
China
Contacts
Shanghai Skin Disease Hospital