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Efficacy and safety of sugammadex in Thoracoscopy thymectomy for Chinese adults with Myasthenia gravis: A prospective randomized controlled study

Application of sugammadex in Chinese adults with myasthenia gravis undergoing thoracoscopy thymectomy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073727
Enrollment
Unknown
Registered
2023-07-19
Start date
2022-08-10
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myasthenia Gravis

Interventions

SUG group:Sugammadex

Sponsors

Beijing Tongren Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1) ASA grade I-III 2) Aged 18 to 65 years 3) BMI 18~28kg/m² 4) Patients with myasthenia gravis undergoing selective thoracoscopic thymectomy 5) Patients who voluntarily participate in the clinical study, and written informed consent should be obtained, able to cooperate with postoperative follow-up

Exclusion criteria

Exclusion criteria: 1) Patients with difficult airways requiring conscious intubation 2) Severe liver and kidney dysfunction 3) Patients with allergies or other contraindications to the investigational drug 4) Patients who take drugs that may affect neuromuscular conduction function or affect muscle relaxation monitoring 5) Pregnant and lactating women

Design outcomes

Primary

MeasureTime frame
Muscle relaxation recovery time;

Secondary

MeasureTime frame
Hemodynamic changes after muscle relaxation antagonism;Incidence of residual muscle relaxation;Extubation time;Residence time in PACU;Adverse reactions;

Countries

China

Contacts

Public ContactHu Chunhua

Beijing Tongren Hospital, Capital Medical University

xueliangchunhuayi@163.com+86 183 1045 4243

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026