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The research of multiple effects for glycine supplementation on non-alcoholic fatty liver disease for medium-short period

The research of multiple effects for glycine supplementation on non-alcoholic fatty liver disease for medium-short period

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073721
Enrollment
Unknown
Registered
2023-07-19
Start date
2023-07-19
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

NAFLD

Interventions

Test group:Glycine

Sponsors

Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Previously diagnosed with fatty liver by ultrasound; 2. Aged greater than 30 years and less than 65 years; 3. Female BMI >= 23 kg/m2 and waist circumference >= 80 cm, male BMI >= 24 kg/m2 and waist circumference >= 85 cm; 4. Male alcohol consumption equivalent to less than 140 g/week of ethanol, female < 70 g/week; 5. Voluntarily participating and signing the informed consent form.

Exclusion criteria

Exclusion criteria: 1. With mental illness; 2. Other liver diseases such as viral hepatitis, drug-induced liver disease, total parenteral nutrition, hepatic steatosis, autoimmune liver disease, or specific diseases that can cause fatty liver; 3. Pregnant or breastfeeding; 4. With diabetes, heart disease, chronic kidney disease, cancer, or taking steroid medications; 5. Underwent cardiovascular disease surgery in the past six months; 6. Unable to guarantee full participation in this project due to time constraints; 7. Taking protein supplements or other nutritional products or medications that regulate glucose and lipid metabolism; 8. Unstable weight in the past three months (weight change >= 4 kg); 9. Unstable place of residence; 10. Patients with low blood pressure.

Design outcomes

Primary

MeasureTime frame
hepatic fat fraction;

Secondary

MeasureTime frame
waist circumference;fast blood glucose;blood pressure;blood lipids;cholestrols;brain imaging;

Countries

China

Contacts

Public ContactRennan Feng

Harbin Medical University

fengrennan@163.com+86 159 4566 7279

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026