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Comparative study of different concentrations of ropivacaine in combination with hydromorphone: effects on rapid rehabilitation after total hip arthroplasty

Comparative study of different concentrations of ropivacaine in combination with hydromorphone: effects on rapid rehabilitation after total hip arthroplasty

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073718
Enrollment
Unknown
Registered
2023-07-19
Start date
2020-12-10
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Femoral neck fracture

Interventions

Group A:Subarachnoid injection of 0.33% ropivacaine 10mg
Group B:Subarachnoid injection of 0.4% ropivacaine 10mg
Group C:Subarachnoid injection of 0.5% ropivacaine 10mg

Sponsors

The Second Hospital of Jilin University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 94 Years

Inclusion criteria

Inclusion criteria: 1) Age = 65 years; 2) physical condition and surgical risk before anesthesia ranged between grades I and III according to the American Association of Anesthesiologists (ASA) classification; 3) BMI, 20-27kg/m2; 4) all patients were examined at admission to confirm tolerance to the trial; 5) not used sedatives, opioids and other analgesics recently; and 6) signed the informed consent form;7) the patients met the diagnostic criteria of “osteonecrosis of femoral head, femoral neck fracture, ankylosing spondylitis in the "Orthopaedic Pathology Diagnostic Specifications";

Exclusion criteria

Exclusion criteria: 1) Unable to cooperate with intraspinal anesthesia and suffer from mental illness; 2) history of spinal surgery, back infection, coagulation dysfunction, or receiving anticoagulant therapy; 3) allergy to local anesthesia drugs, and 4) failed intraspinal anesthesia ; 5)the patient had a medical history or other experimental history in the 3 months prior to the study; 6 ) the patient's tolerance to the experiment is low, and there are subjective factors that can not accept the follow-up investigation or follow-up.

Design outcomes

Primary

MeasureTime frame
Time of hospitalization;Time to get out of bed from the end of surgery;Duration of motor block;

Secondary

MeasureTime frame
effect of anesthesia;

Countries

China

Contacts

Public ContactTian Dan

The Second Hospital of Jilin University

173233639@qq.com+86 155 2685 2169

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026