None listed
Conditions
Interventions
Liposomal bupivacaine group (group LB):A local anesthetic (mixed with bupivacaine liposome 10ml and 0.25% bupivacaine 12ml) was injected adjacent to the infiltrating wound.
Ropivacaine hydrochloride group (group RH):A local anesthetic (0.5% ropivacaine hydrochloride 20ml ) was injected adjacent to the infiltrating wound
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1: Age 18-80 years old, ASA grade I to III, signed informed consent to undergo elective open posterior lumbar decompression and instrumental interbody fusion.
Exclusion criteria
Exclusion criteria: 1: Emergency surgery, allergy to narcotic drugs or history of substance abuse, active infection, primary or metastatic spinal malignancy, lumbar spine fracture, impaired cardiovascular function, or severe liver diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS pain score at rest 24h after surgery.;Postoperative ward remedial analgesic use;QoR-15 scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain scores at VAS at rest 48 and 72 hours after surgery;ain scores of VAS at 24h, 48h and 72h after surgery during exercise or cough;Consumption of postoperative opioid analgesics;Postoperative hospital stay; | — |
Countries
China
Contacts
Public ContactLiu Qing
Department of Anesthesiology, the First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed