Effects of different anesthesia induction methods on perioperative hemodynamics and postoperative rehabilitation: a randomized controlled, multicenter trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300073713

Enrollment

Unknown

Registered

2023-07-19

Start date

2023-10-08

Completion date

Unknown

Last updated

2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

midazolam group:Midazolam anesthesia induction dose 0.05 mg/kg

control group:Intravenous injection of physiological saline of equal volume during induction of general anesthesia

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1: Aged 18-65 years old, ASA classification I-III 2: Planning to undergo surgery under general anesthesia 3: Able to sign the informed consent 4: Able to read and write 5: Nitrogen drugs.

Exclusion criteria

Exclusion criteria: 1: Those who cannot communicate effectively with the researchers 2: Patients with a history of traumatic brain injury, psychiatric history, taking drugs that affect the spirit or nervous system 3: Emergency surgery 4: Patients with incomplete information.

Design outcomes

Primary

Measure	Time frame
Blood pressure (including systolic, diastolic and mean arterial pressure);heart rate;Operation time, recovery time, extubation time, duration in PACU;Awakening score;anxiety;	—

Secondary

Measure	Time frame
EEG Bispectrum Index;Blood sugar, cortisol, epinephrine;Cognitive function;post traumatic stress;intraoperative awareness;At the 3rd and 6th months after surgery;	—

Countries

China

Contacts

Public ContactXie Yubo

The First Affiliated Hospital of Guangxi Medical University

xybdoctor@163.com+86 139 7712 1557

Outcome results