Restless legs syndrome
Conditions
Interventions
patients with RLS:No intervention in this study.
Healthy control group:N/A
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: (1) Patients with RLS: the symptoms of the consultation met the diagnostic criteria of ICSD-3. (2) Healthy subjects: healthy, no complaints of sleep disorders (e.g., insomnia, narcolepsy, restless legs syndrome, etc.), no OSA (i.e., AHI < 5 /hour), periodic limb movements (PLMI < 15 /hour) or other sleep disorders as indicated by overnight PSG monitoring.
Exclusion criteria
Exclusion criteria: Exclusion criteria for RLS patients: (i) physical diseases such as severe cardiovascular diseases, endocrine system diseases, severe hepatic and renal diseases, and neurodegenerative diseases; (ii) severe psychiatric disorders: such as depressive disorders, generalized anxiety disorder, and bipolar disorder; (iii) currently taking psychoactive drugs; (iv) treated RLS; and (v) women in pregnancy or lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| percentage of NREM sleep;percentage of REM sleep;Arousal Index;PLMSI;sleep latency;REM latency;Serum 25-hydroxyvitamin;Serum vitamin B12;Psychomotor vigilance test;Cytokines; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum iron;Serum ferritin; | — |
Countries
China
Contacts
Public ContactYe Zhang
West China Hospital, Sichuan University
Outcome results
None listed