irritable bowel syndrome-D
Conditions
Interventions
control group:Routine treatment
Sponsors
Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age: 18-75 years old; 2. Those who meet the Rome IV diagnostic criteria for IBS-D and have a moderate or higher severity, i.e. an IBS Severity Scoring System (IBS-SSS) score of>=175 points; 3. Junior high school education or above; 4. The patient or family member has no language communication barriers; 5. Able to sign and provide written informed consent; 6. Patients who are willing to participate in SDM, but if assigned to the control group, can also cooperate with the doctor's decision; 7. I hope to receive treatment.
Exclusion criteria
Exclusion criteria: 1. After excluding organic factors, the patient decides not to treat temporarily, that is, patients with mild symptoms (IBS-SSS<175 points). 2. Serious comorbidities that affect medication (such as severe liver dysfunction, renal failure, and congestive heart failure); 3. The presence of celiac disease, IBD, and/or other organic gastrointestinal diseases; Or diseases that affect gastrointestinal motility (such as cholecystitis, pancreatitis, hyperthyroidism, diabetes, chronic renal insufficiency, nervous system diseases, but anxiety and depression are not excluded indicators). 4. Previous gastrointestinal malignancies and/or surgeries (excluding appendectomy or cholecystectomy with a surgical duration of more than 6 months prior to enrollment); 5. Pregnancy or lactation period; 6. Excessive drinking or drug use; 7. The drugs currently used include corticosteroids or anti-inflammatory drugs, proton pump inhibitors, and antibiotic therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| severity of irritable bowel symptoms; | — |
Secondary
| Measure | Time frame |
|---|---|
| evaluation of impact of disease and quality of life;evaluation of negative psychology;Evaluation of diagnosis and treatment process; | — |
Countries
Beijing
Contacts
Public ContactDong Wu
Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences
Outcome results
None listed