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Effect of esketamine as adjuvant on breakthrough pain after interscalene brachial plexus block

Effect of esketamine as adjuvant on breakthrough pain after interscalene brachial plexus block

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073678
Enrollment
Unknown
Registered
2023-07-18
Start date
2022-02-01
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Unilateral radius fracture

Interventions

0.375% Ropivacaine 30ml Nerve Block Group (RS):0.375% ropivacaine 30ml was administered for interscalene brachial plexus block
20mg esketamine combined with 0.375% ropivacaine 30ml nerve block group (RE):20mg esketamine combined with 0.375% ropivacaine 30ml was administered for interscalene brachial plexus block

Sponsors

904th Hospital of the Joint Logistic Support Force
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 78 Years

Inclusion criteria

Inclusion criteria: Patients with unilateral radial fracture undergoing open reduction and internal fixation under interscalene brachial plexus block anesthesia were of all genders, aged 18-78 years, BMI 18-30kg /m², ASA grade I or II.

Exclusion criteria

Exclusion criteria: Patients with multiple injuries with abnormal coagulation function, puncture site infection, allergy to local anesthetics or general anesthetics, and other operations, preoperative neurological damage, cognitive dysfunction, or mental system diseases, were unable to cooperate, and the researchers considered it inappropriate to be included in the study.

Design outcomes

Primary

MeasureTime frame
Block the occurrence of breakthrough pain within 48 h of administration;Duration of breakthrough pain within 48 h of block administration;

Secondary

MeasureTime frame
Sensory block time within 48 h of administration;Drug dosage of analgesic pump for 48 h blocked administration;VAS pain scores at rest and activity before surgery and 8, 12, 24, and 48h after nerve block administration;Sleep quality on the night of surgery: Athens Insomnia Scale;

Countries

China

Contacts

Public Contactlijiaying

904th Hospital of the Joint Logistic Support Force

1875447326@qq.com+86 132 1857 7211

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026