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Effect of Dexmedetomidine combined with ultrasound-guided anterior quadratus lumborum block at the lateral supra-arcuate ligament on postoperative delirium in older adult patients undergoing laparoscopic liver resection: A Prospective Randomized Controlled Clinical Trial

Effect of Dexmedetomidine combined with ultrasound-guided anterior quadratus lumborum block at the lateral supra-arcuate ligament on postoperative delirium in older adult patients undergoing laparoscopic liver resection: A Prospective Randomized Controlled Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073671
Enrollment
Unknown
Registered
2023-07-18
Start date
2023-08-01
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver

Interventions

Group DQG:Combination of dexmedetomidine and quadratus lumbar block
Group QG: Quadratus Lumbar block
Group GA:general anesthesia only

Sponsors

The second hospital, Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 85 Years

Inclusion criteria

Inclusion criteria: This study was approved by the ethics committee of the second hospital of Shandong University; all patients signed informed consent, patients with Laparoscopic hepatectomy patients, age raged from 60-85 years, ASA grade I-III.

Exclusion criteria

Exclusion criteria: 1. Preoperative delirium or dementia; 2. Unable to communicate verbally; 3. Other diseases, such as schizophrenia and depression; 4. History of allergies to research drugs; 5. History of severe hypertension or heart disease; 6. BMI>30kg/m^2; 7. Distant organ metastasis; 8. Recent use of antidepressants, sedatives or analgesics; 9. History of previous abdominal surgery; 10. Recent history of radiotherapy and chemotherapy; 11. Intraoperative operation was changed to open operation; 12. In patients undergoing nerve block, there were regional block complications such as puncture site injury, infection and bleeding and local anesthetic poisoning; 13. Failed to complete data collection.

Design outcomes

Primary

MeasureTime frame
postoperative delirium;

Secondary

MeasureTime frame
NRS;Perioperative opioid consumption;

Countries

China

Contacts

Public ContactChang Feng

The second hospital, Shandong University

fengc2016@126.com+86 531 8587 5957

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026