Breast cancer
Conditions
Interventions
Control group:Usual cancer care
Sponsors
Beijing Chaoyang Sanhuan Cancer Hospital
Eligibility
Sex/Gender
Female
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: ? primary breast cancer (stage I-IIIC) with (neo) adjuvant anthracycline-based chemotherapy ? Age = 18 years old, 18.5 = BMI = 31.9 ? No brain or bone metastasis ? non-secondary breast cancer ? There were no absolute contraindications to exercise 6) no known major structural heart disease, including symptomatic ischemic heart disease, severe valvular disease, or hereditary cardiomyopathy, and no pulmonary, neurologic, respiratory, or renal defects ? Willing to sign the informed consent and be able to participate in the experiment (KPS physical status score 90)
Exclusion criteria
Exclusion criteria: ? Without anthracycline chemotherapy, complicated with other cancers besides breast cancer, stage ? ? Age < 18 years old, BMI = 32 or BMI < 18.5 ? bone and/or brain metastases ? Secondary breast cancer ? absolute exercise contraindications ? known severe structural heart disease, including symptomatic ischemic heart disease, severe valvular disease, or hereditary cardiomyopathy, with pulmonary disease, neurologic disease, or respiratory or renal defects. ? Unwilling to sign the informed consent form, unable to participate in the whole experiment (KPS performance status score < 90)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NT-proBNP;CK-MB;VEGF;Echocardiography;Cardiopulmonary function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional Assessment of Cancer Therapy-Breast;Cancer Fatigue Scale;Wexner constipation score;Zung self-rating Anxiety Scale;Zung self-rating Depression Scale;Pittsburgh Sleep Quality Index;Bone Marrow suppression;Gastrointestinal reactions;Adverse events;Adherence to exercise;Health-related fitness;Amount of physical activity; | — |
Countries
China
Contacts
Public ContactZhang Yimin; Zhang Yurong
Beijing Chaoyang Sanhuan Cancer Hospital
Outcome results
None listed