persistent atrial fibrillation
Conditions
Interventions
treatment group :Nifekalant
Control group:DC cardioversion
Sponsors
The Second Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients with symptomatic persistent or long-duration nonvalvular atrial fibrillation (persistent or long-duration atrial fibrillation confirmed by preoperative routine 12-lead ECG or Holter) 2. Unwilling to take oral antiarrhythmic drugs or ineffective to at least one oral antiarrhythmic drug 3. Be willing to undergo radiofrequency ablation of an atrial fibrillation catheter between the ages of 18 and 80 and agree to a written informed consent 4. Persistent atrial fibrillation after circumferential pulmonary vein vestibular isolation
Exclusion criteria
Exclusion criteria: 1. patients who previously performed radiofrequency ablation of atrial fibrillation 2. The diameter of the left atrium (LA) >55mm 3. Left atrial appendage thrombus 4. Patients with valvular heart disease, hyperthyroidism, severe structural heart disease and previous surgical history 5. There are contraindications to oral anticoagulant therapy or antiarrhythmic drugs 6. patients who had atrial septal defect repair or had an ASD/PFO occluder 7. NYHA IV 8. LVEF<30% 9. Life expectancy with other serious diseases is less than 2 years 10. Patients who lost to follow-up after initial catheter ablation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| atrial fibrillation recurrence; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of postoperative complications;operative time;X-ray exposure time; | — |
Countries
China
Contacts
Public ContactLi Juxiang
The Second Affiliated Hospital of Nanchang University
Outcome results
None listed