Intervertebral disc degenerative disease
Conditions
Interventions
Allograft intervertebral disc transplantation group:N/A
Anterior Cervical Discectomy and Fusion group:N/A
Cervical disc arthroplasty group:N/A
Sponsors
the Sixth Medical Center of PLA General Hospital
Eligibility
Sex/Gender
All
Age
30 Years to 64 Years
Inclusion criteria
Inclusion criteria: ? Cervical disc degeneration accompanied by obvious clinical symptoms, including cervical spondylotic myelopathy, cervical spondylotic radiculopathy, or mixed cervical spondylosis; ? There are obvious positive signs: pathological signs or active tendon reflex, positive Hoffmann sign, unstable walking, etc; ? Cervical disc herniation significantly compresses the spinal cord or nerve root, including degenerative disc herniation and traumatic disc herniation; ? Single segment traumatic cervical spinal cord injury without vertebral fracture and dislocation; ? The lesions mainly accumulate in a single segment, with the lesion segment being C3-C7; ? Pre operative cervical magnetic resonance imaging revealed obvious signs of spinal cord and nerve root compression, which corresponded to clinical symptoms and signs; ? Except for cervical trauma, it was ineffective after Conservative management for at least 6 weeks;
Exclusion criteria
Exclusion criteria: ? Patients with developmental cervical spinal stenosis; ? Patients with severe ossification of the posterior longitudinal ligament; ? Cervical kyphosis deformity; ? There is obvious instability in the responsible section; ? The height loss of the responsible segment intervertebral disc exceeds 20%; ? Patients with active infections, tumors, vertebral fractures, and metabolic bone diseases in the neck; ? Previous cervical spine surgeries
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neck Disability Index (NDI);Range of Motion (ROM);the ratio value of the grayscale (RVG); | — |
Secondary
| Measure | Time frame |
|---|---|
| Japanese Orthopaedic Association Scores (JOA);the Visual Analog Scale (VAS);The Short form health survey-36 (SF-36);disc height index (DHI); | — |
Countries
China
Contacts
Public ContactDike Ruan
the Sixth Medical Center of PLA General Hospital
Outcome results
None listed