A clinical study on ultrasound-guided continuous thoracic paravertebral nerve block combined with pregabalin in the post-thoracotomy pain syndrome

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300073641

Enrollment

Unknown

Registered

2023-07-17

Start date

2023-07-05

Completion date

Unknown

Last updated

2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-thoracotomy pain syndrome

Interventions

patient-controlled intravenous analgesia (PCIA):The postoperative intravenous PCA pump is composed of 100ug sufentanil and 8mg ondansetron, dissolved in 100ml of 0.9% sodium chloride solution, the bas

continuous paravertebral nerve (TPVB) :In the lateral position (the side with the chest open facing upwards), with the back arched and bent, a thoracic paravertebral nerve block on the affected side w

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: ?Age =18 years old and =65 years old; ?ASA classification II~III; ? Elective lung resection (lobectomy, segmentectomy for benign or malignant disease, and wedge resection) and intends to perform surgery through VATS;

Exclusion criteria

Exclusion criteria: ?Patients with PVB contraindications (skin infection, increased intracranial pressure, uncorrectable coagulopathy, anticoagulant therapy and need for bridging therapy (CHADS2-VASc=8), sepsis and spinal cord injury); ?A history of allergy to local anesthetics. ? Morbidly obese (BMI = 40); ?Patients with major heart, lung, liver, kidney, endocrine or blood diseases; ?Patients who have used opioids for a long time for reasons not related to surgery; ?Patients suffering from mental illness; ? People with a history of chronic pain syndrome, such as fibromyalgia, because it can enhance the patient's sensitivity to pain; ?Those who have a history of chest tumor surgery in the past five years; and those who have recurrence of chest tumor within 3 months; ? Severe bleeding during and after surgery or requiring long-term (> 18 hours) mechanical ventilation after surgery; ?Patients converted to thoracotomy during operation and double pneumonectomy excluded;

Design outcomes

Primary

Measure	Time frame
the assessment for the possible emergence of PTPS;Pain scores The numerical rating scale ;	—

Secondary

Measure	Time frame
Rescue analgesia in the PACU;Rescue analgesia in the ward;Analgesia-induced side effects and postoperative pulmonary complications.;	—

Countries

China

Contacts

Public ContactChi Xinjin

The Seventh Affiliated Hospital, Sun Yat-sen University KY

chixinjin@yeah.net+86 139 0301 0076

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026