Peritoneal dialysis
Conditions
Interventions
New peritoneal dialysis group:N/A
Long-term peritoneal dialysis group:N/A
Peritoneal dialysis-related peritonitis group:N/A
Sponsors
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Subjects sign informed consent and cooperate with the study; 2. Subjects aged 18-80 years; 3. Patients with end-stage renal disease were diagnosed according to the Evaluation and management of chronic kidney disease: synopsis of the kidney disease: improving global outcomes 2012 clinical practice guideline; 4. Subjects undergoing dialysis catheterization in our hospital were regularly followed up at our peritoneal dialysis center to maintain stable peritoneal dialysis; 5. All patients with peritoneal dialysis-associated peritonitis met the diagnostic criteria of peritoneal dialysis-associated peritonitis in the International Association for Peritoneal Dialysis's "ISPD Peritonitis Guideline Recommendation: Prevention and Treatment Update 2022"; 6. Subjects with complete clinical data and able to complete relevant statistical analysis of this study.
Exclusion criteria
Exclusion criteria: 1. Those who do not meet the inclusion criteria; 2. Patients with unstable conditions, complicated with serious chronic diseases of the heart, brain, liver, gastrointestinal tract, tumors, blood diseases and severe infectious diseases; 3. Patients with acute renal failure; 4. Refractory peritonitis, fungal/tuberculous peritonitis; 5. Patients undergoing hemodialysis at the same time or undergoing hemodialysis, plasmapheresis or hemofiltration within 3 months; 6. Patients whose mental state cannot cooperate with observation; 7. Pregnant or lactating women; 8. Patients who have taken probiotics and other microecological regulators, antibiotics and immunosuppressants in the past two weeks; 9. Patients with a history of abdominal trauma, gastrointestinal endoscopy or surgery in the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| peritoneum resident macrophages;blood fat; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intestinal microflora communities and metabolites of intestinal microflora;Peritoneal dialysate inflammatory factors;blood routine examination; | — |
Countries
The People's Republic of China
Contacts
Public ContactChen Jiang
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Outcome results
None listed