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Multicenter, randomized controlled, single-blind clinical trial to evaluate the effectiveness of different filling materials for lateral maxillary sinus lift

Multicenter, randomized controlled, single-blind clinical trial to evaluate the effectiveness of different filling materials for lateral maxillary sinus lift

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073635
Enrollment
Unknown
Registered
2023-07-17
Start date
2023-08-01
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Insufficient bone mass in posterior maxillary region

Interventions

Group A: Control group, Bio-Oss bone meal was implanted during external maxillary sinus lift
:Bio-Oss bone meal was implanted during external maxillary sinus lift
Group B: Iliorui bone powder was implanted during external maxillary sinus lift:Iliorui bone powder was implanted during external maxillary sinus lift
Group C: Plasma matrix bone fragments made of iliorui bone meal and plasma matrix were implanted during external maxillary sinus lift
:Plasma matrix bone fragments made of iliorui bone meal and plasma matrix were implanted during external maxillary sinus lift
Group D: Bio-Oss bone meal and plasma matrix bone pieces were implanted during external maxillary sinus lift.:Bio-Oss bone meal and plasma matrix bone pieces were implanted during external maxillary s

Sponsors

Stomatology Hospital of Wuhan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Age 18-70 years old (including 18 and 70 years old), gender is not limited; (2) The patient had at least one missing tooth in the maxillary posterior region that required implantation (14-17, 24-27); (3) The available alveolar bone height in the missing tooth area of the patient is less than 4 mm; (4) The alveolar bone width in the missing area of the patient was =6 mm; (5) Missing teeth for more than 3 months; (6) The patient voluntarily participated in the experiment and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1) full mouth edentulous jaw; (2) maxillary sinus disease or previous maxillary sinus surgery; Severe perforation of maxillary sinus mucosa occurred during operation. (3) The patient has a blood disease; (4) severe kidney and/or liver disease; Congenital or acquired immunodeficiency; (5) Patients who are receiving radiotherapy or chemotherapy at the time of initial diagnosis; (6) Head and neck tumors; (7) Oral mucosal diseases; (8) pregnant and intended pregnant women of childbearing age and breastfeeding women; A male patient whose spouse intends to become pregnant; (9) Poor oral hygiene and poor patient compliance; (10) Tobacco abuse (daily > 20 cigarettes) or binge drinking (> 40mL of alcohol per day); (11) Patients with poorly controlled diabetes (fasting blood glucose > 6.8mmol/L) and poorly controlled hypertension (systolic blood pressure =160mmHg and/or diastolic blood pressure =100mmHg); (12) is undergoing oral or parenteral administration of bisphosphonate therapy; (13) Patients with acute periapical inflammation, progressive periodontal disease, refractory periodontitis history, infection, etc.; (14) Patients with other systemic diseases of the whole body, resulting in patients who cannot receive implant treatment. (15) Other patients determined by the investigator to be unsuitable for inclusion.

Design outcomes

Primary

MeasureTime frame
New bone formation rate;Graft residue rate;

Countries

China

Contacts

Public ContactYufeng Zhang

Hospital of Stomatology, Wuhan University

zyf@whu.edu.cn+86 186 0719 8656

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 3, 2026