Diseases or conditions that require gastroscopy under sedation
Conditions
Interventions
experimental group:CONCERT-CLE closed-loop infusion of propofol
control group:intermittent manual infusion of propofol
Sponsors
Changhai Hospital, Naval Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1: Acception of gastroscopy under sedation 2: Voluntary participation and comprehension of informed consent
Exclusion criteria
Exclusion criteria: 1: American Society of Anesthesiologists (ASA) Classification >II 2: Obstruction of upper digestive tract 3: Severe liver and/or kidney dysfunction 4: Obesity (BMI=28kg/m2) and anticipated difficult airway 5: Respiratory diseases including infection of upper respiratory tract, asthma and chronic obstructive pulmonary disease 6: Arrythmia and NYHA classification >2 7: Psychiatric diseases, use of psychotropic drugs or chronic alcoholism 8: Allergy to propofol or emulsifier
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pulse oxygen saturation;Non-invasive blood pressure;Heart rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Satisfaction of the operating physician;Propofol dosage;bucking;Incidence of intraoperative body movement;emergence time;cerebral state index; | — |
Countries
China
Contacts
Public ContactWang Jiafeng
Faculty of Anesthesiology, Changhai Hospital, Naval Medical University
Outcome results
None listed