koa
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Comply with the diagnostic criteria for knee osteoarthritis in the Guidelines for the Diagnosis and Treatment of Osteoarthritis (2007 edition) formulated by the American Rheumatic Association and the Orthopedic Branch of the Chinese Medical Association in 1995; Age: 45 to 75 years old, regardless of gender; (3) Two weeks before enrollment, the average NRS score of knee joint pain was > 3 points; (4) Disease grading, KOA imaging grading (Kellgren Lawrence, KL) ?-? levels; (5) No pain relieving drugs or acupuncture and moxibustion treatment in recent 2 weeks; Agree to participate in this study and sign an informed consent form. Only those who meet the above 6 criteria can be included in the study.
Exclusion criteria
Exclusion criteria: (1) History of knee surgery or are waiting for knee surgery (such as knee Joint replacement or knee Arthroscopy surgery); ? Knee joint pain caused by other diseases (such as severe joint effusion, malignant tumors, autoimmune diseases, trauma, and infections). (3) Individuals with obvious knee joint deformities such as eversion; (4) Individuals with a history of vascular and nerve injury in the affected limb; (5) Those with severe diseases such as cardiovascular, cerebrovascular, liver, kidney, and hematopoietic systems; (6) History of intrasegmental injection in the target joint in the past 6 months (7) Pregnant and lactating women patients;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| average pain NRS scores;Young's modulus of Quadriceps; | — |
Secondary
| Measure | Time frame |
|---|---|
| WOMAC function subscale scores;SF-12 Quality of Life Survey Scale; | — |
Countries
China
Contacts
Shandong Provincial Third Hospital, Shandong University