Application of early comprehensive pulmonary rehabilitation in patients with acute exacerbation of chronic obstructive pulmonary disease

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300073606

Enrollment

Unknown

Registered

2023-07-17

Start date

2023-07-17

Completion date

Unknown

Last updated

2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute exacerbation of chronic obstructive pulmonary disease

Interventions

experimental group:On the basis of control group + external diaphragm pacing treatment + high-frequency vibration sputum + resistance training

control group:Routine treatment and nursing + respiratory muscle training + cough and expectoration training

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: ? Meeting the diagnostic criteria of the Global Initiative for the Prevention and Control of Chronic Obstructive Pulmonary Disease 2019 (GOLD2019) ? Age 18-80 years old, gender unlimited ? It can maintain the stable and acute exacerbation of chronic obstructive pulmonary disease with conventional drug treatment ?It can cooperate with sports training, respiratory training, sputum expulsion training, health education and evaluation index detection ? can clearly express their wishes, and voluntarily join the lung rehabilitation training.

Exclusion criteria

Exclusion criteria: ? with other chronic respiratory diseases, such as malignant tumors, tuberculosis, bronchial asthma, pulmonary interstitial fibrosis, etc. ? Patients requiring invasive ventilator support treatment, severe electrolyte disturbance or unstable vital signs (3) Patients with stable COPD who could not carry out mild exercise or needed to stay in bed completely due to other physical diseases and could not complete the 6min walking test (4) Patients with severe Heart failure were classified asNew York Heart Association, grade ?. (5) There are muscle, bone or neuropathy affecting pulmonary rehabilitation treatment ? Past 3 months to participate in lung rehabilitation training.

Design outcomes

Primary

Measure	Time frame
6 minutes walk distance;	—

Secondary

Measure	Time frame
Arterial oxygen partial pressure;Arterial carbon dioxide pressure;Leukocyte count;Procalcitonin;m MRC;COPD Assessment T;Hospital Anxiety and Depression Scale;Pittsburgh Sleep Quality Index;	—

Countries

China

Contacts

Public ContactSilin Zhen

Affiliated Hospital of Southwest Medical University

1400223549@qq.com+86 130 0286 6667

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026