peritoneal dialysis-related peritonitis
Conditions
Interventions
Western medicine group:According to the 2022 ISPD guidelines, the empirical antibiotic regimen covered gram-positive and gram-negative bacteria, and cefazolin sodium and cefoperazone sodium and sulbac
Fushen Formula group:On the basis of the treatment plan of the western medicine group, Fushen formula (10g Tangerine peel, 15g Qingpinellia, 15g Epimedium, 30g salvia miltiorrhiza, 10g angelica, 15g a
Sponsors
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Subjects sign informed consent and cooperate with the study; 2. Subjects aged 18-80 years; 3. Patients with end-stage renal disease were diagnosed according to Evaluation and management of chronic kidney disease: synopsis of the kidney disease: improving global outcomes 2012 clinical practice guideline; 4. Subjects undergoing dialysis catheterization in our hospital were regularly followed up at our peritoneal dialysis center to maintain stable peritoneal dialysis; 5. Subjects with complete clinical data and able to complete relevant statistical analysis of this study; 6. No Chinese medicine or proprietary medicine taken within 2 weeks; 7. Meeting the diagnostic criteria for peritoneal dialysis-associated peritonitis; 8. The syndrome type of TCM is spleen and kidney qi deficiency.
Exclusion criteria
Exclusion criteria: 1. Those who do not meet the inclusion criteria; 2. Patients with unstable conditions, complicated with serious chronic diseases of the heart, brain, liver, gastrointestinal tract, tumors, blood diseases and severe infectious diseases; 3. Patients undergoing hemodialysis at the same time or undergoing hemodialysis, plasmapheresis or hemofiltration within 3 months; 4. Patients whose mental state cannot cooperate with observation; 5. Patients with acute renal failure; 6. According to the researchers' judgment, the patient had other conditions that were not suitable for inclusion; 7. Refractory peritonitis, fungal/tuberculous peritonitis, etc.; 8. Pregnant or lactating women; 9. Patients who have taken probiotics and other microecological regulators, antibiotics and immunosuppressants in the past two weeks; 10. Patients with a history of abdominal trauma, gastrointestinal endoscopy or surgery in the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TCM clinical syndrome scoring scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| liver function;renal function;blood fat;eritoneal dialysate cell detection;peritoneum resident macrophages;Intestinal microflora communities and metabolites of intestinal microflora;Peritoneal dialysate inflammatory factors;blood routine examination;Serum electrolytes; | — |
Countries
the People's Republic of China
Contacts
Public ContactChen Jiang
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Outcome results
None listed