major depressive disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Meet the diagnostic criteria for depression in DSM-?; 2)18-60 years old, Han nationality, right-handed; 3) First episode, no previous use of psychotropic drugs; 4) Clinical treatment is consistent with this study protocol
Exclusion criteria
Exclusion criteria: 1) Patients with serious physical or neurological diseases; 2) any other mental disorder with a DSM-IV diagnosis; 3) There are metal objects in the body (such as metal dentures, cardiac pacemakers, etc.) affecting the MRI examination; 4) Color blindness can not effectively complete the test
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 17-item Hamilton Depression Scale (HAMD-17);Head MRI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Wechsler Adult Intelligence Scale;The Cambridge Neuropsychological Automated Test Battery; | — |
Countries
China
Contacts
West China Hospital of Sichuan University