tonsillectomy and adenoidectomy
Conditions
Interventions
A group:In group A, 0.3mg/kg esketamine was injected intravenously during induction, and normal saline was pumped at 0.5mg/kg·h during operation.
B group:In group B, 0.3mg/kg normal saline was injected intravenously during induction, and esketamine was pumped at 0.5mg/kg·h during operation
C group:In group C, 0.3mg/kg normal saline was injected intravenously during induction, and the normal saline was pumped at 0.5mg/kg·h during operation
Sponsors
Affiliated Hospital of North Sichuan Medical College
Eligibility
Sex/Gender
All
Age
4 Years to 12 Years
Inclusion criteria
Inclusion criteria: Children with tonsil or adenoid hypertrophy were selected, aged 4 ~ 12 years. BMI 18-28 kg/m2; ASA Class I -II; Preoperative physical examination showed no abnormality in cardiopulmonary function and normal liver and kidney function.
Exclusion criteria
Exclusion criteria: A history of allergy to opioid or non-opioid analgesics, a history of respiratory infections, asthma, developmental delays, or psychiatric disorders associated with irritability, anxiety, attention deficit, sleep disturbance, or cognitive impairment, children with difficulty in the preoperative assessment, or those unable to complete the trial for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative recovery quality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Scores of agitation during anesthesia recovery in children;Postoperative pain score;Extubation time;Intraoperative use of remifentanil;Adverse reaction; | — |
Countries
China
Contacts
Public ContactJingyan Lin
Affiliated Hospital of North Sichuan Medical College
Outcome results
None listed