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Efficacy of iTBS double target stimulation in upper limb function recovery of subacute stroke patients

Efficacy of iTBS double target stimulation in upper limb function recovery of subacute stroke patients

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073593
Enrollment
Unknown
Registered
2023-07-15
Start date
2023-07-15
Completion date
Unknown
Last updated
2023-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

experimental group:Both the primary somatosensory cortex and the primary motor cortex on the affected side received intermittent burst stimulation
Control group 1:The primary somatosensory cortex of the affected side received intermittent burst stimulation, and the primary motor cortex of the affected side received pseudo-intermittent burst stim
Control group 2:The primary somatosensory cortex of the affected side received pseudo intermittent burst stimulation, and the primary motor cortex of the affected side received intermittent burst stim

Sponsors

Shanghai ZhongYe Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 79 Years

Inclusion criteria

Inclusion criteria: ? Patients aged between 40 and 79 years, diagnosed with subacute ischemic or hemorrhagic stroke [3-24 weeks], with the first onset; (2) The upper limb Fugl-Meyer Assessment (FMA) exercise score (0-66) was between 10-62; ?(Mini Mental State Examination-MMSE score=18).

Exclusion criteria

Exclusion criteria: ? serious bone, joint and muscle disorders; Liver, kidney and other serious life-threatening diseases and mental patients; ? Those who do not accept the treatment plan; ? Currently participating in other clinical trials; A history of multiple brain injury, other related neurological disorders, peripheral sensory dysfunction, or psychiatric disorders, including drug and alcohol abuse; Participants who were also receiving upper limb therapy, had contraindications to iTBS, and were using medications that could affect cortical excitability were also excluded.

Design outcomes

Primary

MeasureTime frame
Upper limb motor function;Revised Nottingham Sensory Assessment Scale;

Secondary

MeasureTime frame
motor evoked potential;Median nerve evoked potential;action research arm test;Modified Ashworth Scale;

Countries

China

Contacts

Public ContactZhu Jianzhong

Shanghai ZhongYe Hospital

328937251@QQ.com+86 136 8166 7417

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026