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Evaluation of antihypertensive efficacy of Esmolol in patients with spontaneous intracerebral hemorrhage

Evaluation of antihypertensive efficacy of Esmolol in patients with spontaneous intracerebral hemorrhage

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300073592
Enrollment
Unknown
Registered
2023-07-15
Start date
2023-07-15
Completion date
Unknown
Last updated
2023-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral hemorrhage

Interventions

Experimental observation group: Esmolol (Recommended dose: Load dose of 0.5mg/kg, followed by intravenous infusion at 0.05mg/kg/min, blood pressure monitoring, observation and Recommended usage and do

Sponsors

Shandong University Qilu Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with spontaneous cerebral hemorrhage according to the Chinese Guidelines for Diagnosis and Treatment of Cerebral Hemorrhage 2019 (i.e. (1) acute onset; (2) Symptoms of functional impairment of the Vesta channel (a few are comprehensive neurological impairment), often accompanied by headache, vomiting, elevated blood pressure and varying degrees of consciousness disorders; (3) Head CT or MRI showing bleeding focus; (4) Non-vascular cerebral causes were excluded. Satisfy the above 4, can be diagnosed as spontaneous cerebral hemorrhage); 2. Age =18 years old, gender unlimited; 3. Patients with blood pressure =140/90mmHg upon arrival at hospital.

Exclusion criteria

Exclusion criteria: 1. Secondary cerebral hemorrhage caused by vascular disease, tumor stroke, etc.; 2. Heart rate below 60bpm; 3. Patients with bronchial asthma or history of asthma and severe COPD; 4. Patients with sluggish antrum and second to third degree atrioventricular block; 5. Cardiac insufficiency or cardiogenic shock; 6. Researchers believe that they cannot be included in the study for other reasons; 7. I refuse to participate in the study.

Design outcomes

Primary

MeasureTime frame
Blood pressure;

Secondary

MeasureTime frame
Heart rate;

Countries

China

Contacts

Public ContactQibin Huang

Shandong University Qilu Hospital

819431886@qq.com+86 136 8143 8245

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026