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Effect of alfentanil on rapid perioperative recovery in day surgery patients —— a randomized, double-blind, clinical comparative study

Effect of alfentanil on rapid perioperative recovery in day surgery patients

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073590
Enrollment
Unknown
Registered
2023-07-14
Start date
2024-04-20
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Daytime hysteroscopy

Interventions

Group C:Fentanyl 4ug/kg induction
Group E1:Alfentanil 20ug/kg induction
Group E2:Alfentanil 30ug/kg induction
Group E3:Alfentanil 40ug/kg induction

Sponsors

Anqing Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients with complete clinical data who are intended to undergo gynecologic hysteroscopic surgery; 2. ASA classification I-II; 3. The patient's age is 20-60 years old; 4. Body mass index (BMI) of 18-28 kg/m2; 5. Clearly understand, voluntarily participate in the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Those who have a history of mental illness, severe depressive state or long-term use of psychotropic drugs; 2. Those with serious preoperative combined heart, brain, liver, kidney and endocrine diseases or immune system diseases; 3. Respiratory system diseases such as combined asthma; 4. Long-term use of sedative and analgesic drugs; 5. Preoperative presence of lung infection, respiratory failure: PaO2<60mmHg or SPO2<92% (when inhaling air); 6. Those who are allergic to opioids and other anesthetic drugs; 7. Patients who have been bedridden for a long time, patients with myasthenia gravis; 8. Those who have been treated with anticoagulant drugs for a long time before surgery; 9. Malignant hyperthermia or with family history.

Design outcomes

Primary

MeasureTime frame
Plasma norepinephrine(NE) levels;

Secondary

MeasureTime frame
Hemodynamic Indicators;Incidence of agitation during awakening;Postoperative pain assessment;Use of analgesics or antiemetics;Dosage of propofol, remifentanil, cisatracurium, and other adjuvant drugs;time statistics;

Countries

China

Contacts

Public ContactJu Xia

Anqing Municipal Hospital

alcon2006@126.com+86 136 8556 3136

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 22, 2026