Gastrointestinal Tumors
Conditions
Interventions
Group interventon:The gastointestinal defects after Endoscopic submucosal dissection (ESD) will be closed using endoscopic hand suturing (EHS) technique
Sponsors
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Endoscopic evaluation of feasible endoscopic submucosal dissection (ESD) for gastrointestinal lesions; (2) The estimated length of the mucosal defect is 20-50mm; (3) 18 years = age = 70 years; (4) The ECOG score is 0-1 points.
Exclusion criteria
Exclusion criteria: (1) Lesions with lymph node metastasis; (2) Patients with poor general condition and inability to tolerate endoscopic surgery; (3) Patients with coagulation dysfunction (platelet count 2) or taking antithrombotic agents, before their coagulation function is corrected; (4) Patients who refuse or are not suitable for surgery; (5) Patients with previous abdominal or pelvic radiation therapy; (6) The 'lifting sign' is negative.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete closure rate of postoperative wounds;Delayed postoperative bleeding rate;Continuous closure rate of postoperative wounds; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bleeding rate during EHS;Perforation rate during EHS;EHS time;Postoperative delayed perforation rate;Incidence of other postoperative adverse events; | — |
Countries
China
Contacts
Public ContactGuiqi Wang
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Outcome results
None listed