Clinical research on esophageal cancer screening based on multi-omics detection

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300073574

Enrollment

Unknown

Registered

2023-07-14

Start date

2021-06-16

Completion date

Unknown

Last updated

2023-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal cancer

Interventions

Esophageal Cancer Group:N/A

Control group:N/A

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1) Age: =18 years old; 2) Samples related to esophageal cancer cases need to be pathologically confirmed as esophageal squamous intraepithelial neoplasia or esophageal squamous cell carcinoma; 3) Cases with normal esophagus are required not to suffer from any malignancy or history of malignancy; 4) In good physical condition, able to tolerate endoscopy and biopsy; 5) The patient has not received radiofrequency, freezing, photodynamic, endoscopic resection, surgery or chemotherapy; 6) Voluntarily sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1) Esophageal adenocarcinoma and its precancerous lesions; 2) Patients who are receiving anticoagulant therapy (such as warfarin, clopidogrel, heparin or aspirin and other anticoagulant drugs are currently or recently used); 3) Patients with myocardial infarction or other serious heart diseases in the past 6 months; 4) Serious cerebrovascular diseases such as cerebral hemorrhage occurred in the past 6 months; 5) The patient has previously received radiofrequency, cryotherapy, photodynamic, endoscopic resection, surgery or chemotherapy for esophageal tumors 6) Combined with mental illness; 7) Those with incomplete clinical data (unclear diagnosis, incomplete medical history data, incomplete medication records, etc.); 8) Pregnancy/lactating period; 9) Unable to sign the informed consent form

Design outcomes

Primary

Measure	Time frame
Sensitivity and specificity of a multi omics detection algorithm model for screening early esophageal cancer patients;	—

Secondary

Measure	Time frame
The predictive accuracy of multi omics detection models for esophageal cancer patients;	—

Countries

China

Contacts

Public ContactGuiqi Wang

National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

wangguiq@126.com+86 136 7122 9223

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026