Gastric cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Gastric cancer patients: 1) Age greater than 18 years old; 2) Gastric cancer cases require no other malignant tumors and no previous history of malignant tumors; 3) The relevant samples of gastric cancer cases should be pathologically confirmed as gastric adenocarcinoma, adenosquamous carcinoma, squamous carcinoma, undifferentiated carcinoma, and neuroendocrine carcinoma; 4) The patient has not received radio frequency, cryotherapy, photodynamic therapy, endoscopic resection, surgical surgery, radiotherapy, or chemotherapy; 5) Good physical condition, able to tolerate gastroscopy and biopsy; 6) Voluntarily sign the informed consent form. Normal population: 1) Normal cases of the stomach require not having any malignant tumors and no previous history of malignant tumors; 2) Good physical condition, able to tolerate gastroscopy and biopsy; 3) Voluntarily sign an informed consent form.
Exclusion criteria
Exclusion criteria: Gastric cancer patients: 1) History of other types of cancer except for gastric cancer; 2) Patients undergoing anticoagulant therapy (such as those who are currently or have recently used anticoagulants such as warfarin, clopidogrel, heparin, or aspirin); 3) Patients who have experienced myocardial infarction or other serious heart diseases in the past 6 months; 4) Have experienced severe cerebrovascular diseases such as cerebral hemorrhage in the past 6 months; 5) The patient has previously received radiofrequency, cryotherapy, photodynamic therapy, endoscopic resection, surgical surgery, or chemotherapy for gastric tumors; 6) Concomitant mental illness; 7) Individuals with incomplete clinical data (unclear diagnosis, incomplete medical history, incomplete medication records, etc.); 8) Pregnancy/lactation period; 9) Treat with proton pump inhibitors or H2 blockers within the first 2 weeks; 10) Family history of cancer; 11) Unable to sign the informed consent form. Normal population: 1) Individuals with incomplete clinical data (unclear diagnosis, incomplete medical history, incomplete medication records, etc.); 2) Pregnancy/lactation period; 3) Treat with proton pump inhibitors or H2 blockers within the first 2 weeks; 4) Having a family history of cancer or other non gastric chronic illnesses; 5) Concomitant mental illness; 6) Unable to sign informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity and specificity of multi omics detection algorithm models for screening gastric cancer patients; | — |
Secondary
| Measure | Time frame |
|---|---|
| Prediction accuracy of multi omics detection models for gastric cancer patients; | — |
Countries
China
Contacts
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College