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Clinical research on gastric cancer screening based on multi-omics detection

Clinical research on gastric cancer screening based on multi-omics detection

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300073572
Enrollment
Unknown
Registered
2023-07-14
Start date
2021-09-07
Completion date
Unknown
Last updated
2023-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer

Interventions

Gastric cancer group:N/A
Control group:N/A

Sponsors

National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Gastric cancer patients: 1) Age greater than 18 years old; 2) Gastric cancer cases require no other malignant tumors and no previous history of malignant tumors; 3) The relevant samples of gastric cancer cases should be pathologically confirmed as gastric adenocarcinoma, adenosquamous carcinoma, squamous carcinoma, undifferentiated carcinoma, and neuroendocrine carcinoma; 4) The patient has not received radio frequency, cryotherapy, photodynamic therapy, endoscopic resection, surgical surgery, radiotherapy, or chemotherapy; 5) Good physical condition, able to tolerate gastroscopy and biopsy; 6) Voluntarily sign the informed consent form. Normal population: 1) Normal cases of the stomach require not having any malignant tumors and no previous history of malignant tumors; 2) Good physical condition, able to tolerate gastroscopy and biopsy; 3) Voluntarily sign an informed consent form.

Exclusion criteria

Exclusion criteria: Gastric cancer patients: 1) History of other types of cancer except for gastric cancer; 2) Patients undergoing anticoagulant therapy (such as those who are currently or have recently used anticoagulants such as warfarin, clopidogrel, heparin, or aspirin); 3) Patients who have experienced myocardial infarction or other serious heart diseases in the past 6 months; 4) Have experienced severe cerebrovascular diseases such as cerebral hemorrhage in the past 6 months; 5) The patient has previously received radiofrequency, cryotherapy, photodynamic therapy, endoscopic resection, surgical surgery, or chemotherapy for gastric tumors; 6) Concomitant mental illness; 7) Individuals with incomplete clinical data (unclear diagnosis, incomplete medical history, incomplete medication records, etc.); 8) Pregnancy/lactation period; 9) Treat with proton pump inhibitors or H2 blockers within the first 2 weeks; 10) Family history of cancer; 11) Unable to sign the informed consent form. Normal population: 1) Individuals with incomplete clinical data (unclear diagnosis, incomplete medical history, incomplete medication records, etc.); 2) Pregnancy/lactation period; 3) Treat with proton pump inhibitors or H2 blockers within the first 2 weeks; 4) Having a family history of cancer or other non gastric chronic illnesses; 5) Concomitant mental illness; 6) Unable to sign informed consent form.

Design outcomes

Primary

MeasureTime frame
Sensitivity and specificity of multi omics detection algorithm models for screening gastric cancer patients;

Secondary

MeasureTime frame
Prediction accuracy of multi omics detection models for gastric cancer patients;

Countries

China

Contacts

Public ContactGuiqi Wang

National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

wangguiq@126.com+86 136 7122 9223

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026