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Comparison of the effects of different concentrations of Ropivacaine combined with dexamethasone in ultrasound guided brachial plexus block: a randomized controlled study

Comparison of the effects of different concentrations of Ropivacaine combined with dexamethasone in ultrasound guided brachial plexus block: a randomized controlled study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073546
Enrollment
Unknown
Registered
2023-07-13
Start date
2023-07-15
Completion date
Unknown
Last updated
2023-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rotator Cuff Injury

Interventions

A:0.25% Ropivacaine 10ml+0.9% normal saline (1ml)
B:0.5% Ropivacaine 10ml+0.9% normal saline (1ml)
C:0.75% Ropivacaine 10ml+0.9% normal saline (1ml)
D:0.25% Ropivacaine 10ml+5mg dexamethasone (1ml)
E:0.5% Ropivacaine 10ml+5mg dexamethasone (1ml)
F:0.75% Ropivacaine 10ml+5mg dexamethasone (1ml)

Sponsors

Liaoning Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients aged 18-80 years who plan to undergo shoulder Arthroscopy surgery with ASA classification I-III

Exclusion criteria

Exclusion criteria: 1. Patients who refused to participate in this study; 2. Infection of the operating site and abnormal anatomy of the site; 3. Study the history of Drug allergy reaction; 4. Systemic use of Corticosteroid for two weeks or more; 5. Peripheral neuropathy, previous musculocutaneous, radial, and ulnar neuropathy; 6. Mental disorders, coagulation disorders; 7. BMI>35kg/m ²; 8. Serious pulmonary diseases (such as acute exacerbation of COPD), cardiac insufficiency (such as EF1.5 times the upper normal limit or GFR<40ml/min); 9. Pregnant or lactating women; 10. Patients who are chronically using opioid drugs.

Design outcomes

Primary

MeasureTime frame
Duration of sensory;Diastolic pressure;

Secondary

MeasureTime frame
Duration of motor block;Demand for analgesics within 24 hours after operation;Patient NRS pain score;The incidence of postoperative nausea and vomiting;Systolic pressure;Mean arterial pressure;Heart rate;Oxygen saturation;BIS;

Countries

China

Contacts

Public ContactChangming Wang

Liaoning Provincial People's Hospital

835606336@qq.com+86 177 0248 6100

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026