Atrophic Acne Scar
Conditions
Interventions
Test side:Mussel Adhesive Proteins
Control side:Desonide cream twice a day (3 days in total), fusidic acid cream twice a day (7 days in total), and recombinant human epidermal growth factor four times a day (7 days in total).
Sponsors
The First Hospital of China Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-60 years old, gender is not limited; 2. Meet the diagnosis of facial atrophic acne scars, and the severity of acne scars on both sides of the face is consistent; 3. The course of the disease is more than 3 months; 4. Those who can persist in completing the treatment and follow-up and have not used other methods of treatment during the period; 5. Subjects participate voluntarily and need to sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. People with photosensitive skin or those who used photosensitive drugs within 4 weeks; 2. Those who have received sun exposure in the past 1 month or may receive sun exposure 1 month after treatment; 3. Those who have used retinoic acid drugs in the past 1 month; 4. There is skin infection at the treatment site, or there are wounds or incisions that have not healed; 5. People with scar constitution; 6. Pregnant or lactating patients; 7. Patients with heart, kidney, liver insufficiency or other serious underlying diseases; 8. Patients with immunodeficiency diseases; 9. Patients with mental illness; 10. Those with unrealistic expectations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VISIA image analysis;transepidermal waterloss, TEWL;Water content of Stratum corneum;Sebum measurement;Skin melanin index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Erythema, edema, degree of pigmentation;comfort evaluation;Scab removal time; | — |
Countries
China
Contacts
Public ContactYan Wu
The First Hospital of China Medical University
Outcome results
None listed