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Correlation assessment and model construction of ultrasound and imaging scores with endoscopic Crohn's disease activity

Correlation assessment and model construction of ultrasound and imaging scores with endoscopic Crohn's disease activity

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300073521
Enrollment
Unknown
Registered
2023-07-13
Start date
2023-07-01
Completion date
Unknown
Last updated
2023-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Crohn's disease

Interventions

Gold Standard:Reference Standard: Clinical Disease Activity Score and Endoscopic Disease Activity Score.
Index test:Ultrasound scoring and magnetic resonance scoring.

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Patients with CD who were clearly diagnosed based on clinical, imaging, endoscopic, and postoperative pathology, and all patients included in the study diagnosed with the diagnostic criteria recommended by the Consensus Opinion on the Diagnosis and Treatment of Inflammatory Bowel Disease (2018*Beijing). (2) Colonoscopy, intestinal ultrasound, and abdominal magnetic resonance were completed within 4 weeks. (3) The examination instruments used for all patients were consistent, and were scored by doctors specialising in endoscopy, ultrasound and imaging, respectively.

Exclusion criteria

Exclusion criteria: (1) Age <18 years, inability to give informed consent, pregnancy, isolated disease of the upper gastrointestinal tract, severe obesity hampering IUS evaluation, ileocolonic anastomosis not recognised at IUS, and active gastroenteritis. If an impassable stricture is identified that prevents endoscopic evaluation of the terminal ileal mucosa, the case will be excluded from the study. (2) Cases that failed to complete all examinations within 4 weeks.

Design outcomes

Primary

MeasureTime frame
Harvey-Bradshaw index;SES-CD;Rutgeerts score;International Bowel Ultrasound Segmental Activity Score;ROC curve;

Countries

China

Contacts

Public ContactYufang Wang

West China Hospital, Sichuan University

wangyufang04@126.com+86 189 8060 1283

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026