Hemodynamics
Conditions
Interventions
Group C:Bupivacaine
group F1 :Bupivacaine + fentanyl 25ug
group 2:Bupivacaine + fentanyl 50ug
Sponsors
Ningxia Hui Autonomous Region People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1) Age = 60 years old and < 90 years old, gender and nationality are not limited; 2) ASA Grade I-III; 3) Proposed lower limb orthopedic surgery; 4) Endospinal anesthesia; 5) Agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Those who refuse to participate in this study; 2) previous bed rest, schizophrenia, epilepsy, Parkinson's history or myasthenia gravis; 3) Those with coagulation dysfunction, history of spinal trauma, lumbar spine lesions that are not easy to undergo neuraxial anesthesia, puncture site infection; 4) Those who cannot communicate due to coma, severe dementia, language disorders, terminal diseases, etc. before surgery; 5) Critical condition (preoperative ASA grade =IV); Severe renal impairment (requiring renal replacement therapy) Severe liver impairment (Child-Pugh class C); severe cardiac insufficiency (NYHA= grade III.); 6) The attending physician or investigator believes that there are other circumstances that are not suitable to participate in this study. The reason needs to be documented.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure;heart rate;Hypotension;hypertension;Bradycardia;tachycardia;Hypothermia;Respiratory depression;Hypoxemia;chill;Itching; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to onset of action of anesthesia;Anesthesia plane;Vasoactive drug use;Amount of bleeding;The amount of blood transfused;Amount of liquid; | — |
Countries
China
Contacts
Public ContactYe Qingshan
Ningxia Hui Autonomous Region People's Hospital
Outcome results
None listed