Osteoarthritis of the knee
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) patients requiring unilateral initial TKA surgery (2) aged =18 years old (3) body mass index was 18~35 kg/m2 (4) the American Society of Anesthesiologists (ASA) classification (anesthesia risk assessment) is I ~ III level (5) the patient signed the informed consent.
Exclusion criteria
Exclusion criteria: (1) there were more than moderate intraoperative knee malformations (pronation and flexion malformations) (2) surgical history of knee joint and surgical limb neuropathy (3) long-term opioid users (opioids were used daily or almost daily for more than 3 months) (4) language impairment and inability to perform pain numrical rating scale, (NRS) (5) Allergy to drug use and regional block contraindications
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total opioid use 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| NRS pain score;postoperative muscle strength;Knee range of motion;adverse event;sleep quality on the night after surgery;the time to first getting out of bed;length of stay;quality of recovery scale (QOR-15 score); | — |
Countries
China
Contacts
West China Hospital, Sichuan University