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To explore the effect of esketamine on recovery agitation and intraoperative opioid consumption in patients undergoing thoracoscopic partial pulmonary resection

To explore the effect of esketamine on recovery agitation and intraoperative opioid consumption in patients undergoing thoracoscopic partial pulmonary resection

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073502
Enrollment
Unknown
Registered
2023-07-12
Start date
2023-06-02
Completion date
Unknown
Last updated
2023-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

waking period restlessness

Interventions

Esketamine group (Group E):Group E was given esketamine 0.5mg/kg before skin incision, and then esketamine 4ug/kg/min
Control group (group C):total intravenous anesthesia

Sponsors

The Second Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Gender is not limited, age 18-65 years old, ASA classification ?~? 2. Voluntarily accept the use of postoperative analgesic pump 3. Thoracoscopic partial lung resection (lung segment, wedge, bullae) 4. Voluntary subjects and signed informed consent

Exclusion criteria

Exclusion criteria: 1. History of allergy to local anesthetics or non-steroidal anti-inflammatory drugs 2. Known coagulation disorders 3. Infection near the puncture 4. History of chronic pain or frequent use of analgesics 5. Patients with communication disorders or other reasons not applicable to this study were excluded 6. There are symptoms of high intracranial pressure or a history of glaucoma.

Design outcomes

Primary

MeasureTime frame
RSS Agitation Score and Ramsay Sedation Score;

Secondary

MeasureTime frame
Extubation quality score;Intraoperative opioid use;Pain score at 0.5h,1h,2h, 4h, 8h, 12h, 24h, 48h after operation;Occurrence of adverse reactions;Analgesic pump use;

Countries

China

Contacts

Public ContactChenqi

The Second Affiliated Hospital of Anhui Medical University

1228022438@qq.com+86 138 6610 3453

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026