Knee osteoarthritis, Overweight/Obese
Conditions
Interventions
Intervention group 2:Progressive resistance exercise intervention for the four major muscle groups + weight-bearing functional training
Intervention group 1:Progressive resistance movement intervention of muscles around the knee joint+weight-bearing functional training
Control group:Progressive resistance exercise intervention for muscles around the knee joint
Sponsors
Peking University School of Public Health
Eligibility
Sex/Gender
All
Age
45 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. 45 years old<=Age<=85 years old; 2. Overweight/obese, 24kg/m^2<=BMI<=35kg/m^2; 3. At least one knee with Kellgren Lawrence grade 2 or 3 osteoarthritis; 4. Numerical rating scale (NRS) 3-7 points on the affected side; 5. Less than 30 minutes of formal exercise per week in the past 6 months; 6. Agree to participate in this study; 7. Clear consciousness and able to cooperate with the intervention.
Exclusion criteria
Exclusion criteria: 1. Severe comorbidities that may hinder safe participation in the intervention; 2. History of acute knee injury; 3. Unwilling or unable to change exercise behavior; 4. Suffering from severe cognitive impairment or depression; 5. Unable to walk without a cane or other assistive devices; 6. Currently participating in other intervention studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difficulity in daily activities; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lower limb muscle strength;knee pain;balance function;Ability to go up and down stairs;indicators of body composition;physical activity;Walking ability;Knee stiffness;Abdominal muscle endurance;Life quility;depressed;Height;Weight;Abdominal girth;Hip circumference;Grip; | — |
Countries
China
Contacts
Public ContactHongbo Chen
Peking University Third Hospital
Outcome results
None listed