Based on multi-omics to explore the biological characteristics of acute gouty arthritis with pattern of dampness-heat toxin amassment and dampness-heat amassment

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300073477

Enrollment

Unknown

Registered

2023-07-12

Start date

2023-07-12

Completion date

Unknown

Last updated

2023-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute gouty arthritis

Interventions

Pattern of dampness-heat toxin amassment Group:No intervention

Pattern of dampness-heat amassment Group:No intervention

Normouricemic Group:No intervention

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic standards of Western medicine for this acute gouty arthritis. 2. Patients who meet the diagnostic criteria for humid heat toxicity certificate and humid heat containment certificate. 3. This visit is an acute onset, and the course of the disease is within 72 hours; 4. The patient voluntarily accepts and cooperates with the examination; 5.18= Age= 65 years old; 6. Patients who have voluntarily participated and signed an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients who have used antibiotics within the past month; 2. Patients who take probiotics or prebiotics and other supplements that can significantly change the Gut microbiota in the past three months; 3. Patients who have diarrhea, bloating, abdominal pain, and other intestinal related diseases in the past two weeks; 4. Patients who complicated with acute infection, severe cardio cerebral Vascular disease and severe liver and kidney function damages; 5. Patients who diagnosed as other rheumatic diseases, including other crystalline arthritis, Cushing's syndrome, etc; 6. Patients with Mental disorder or poor compliance; 7. Pregnant or lactating women; 8. Patients who are currently participating in or have participated in other clinical trials within a month; 9. Researchers determine that patients have poor compliance and are unable to complete the experiment

Design outcomes

Primary

Measure	Time frame
renal function;ESR;crp;Peripheral blood biomarkers;Intestinal flora;	—

Secondary

Measure	Time frame
cholesterol;triglyceride;HDL-C;LDL-C;GLU;liver function;Blood routine;urinalysis ;	—

Countries

China

Contacts

Public ContactWei Liu

First Teaching Hospital of Tianjin University of Traditional Chinese Medicine

731740792@qq.com+86 135 1616 1000

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026