Effects of sleep deprivation on memory reconsolidation in alcohol addiction and its neural mechanism

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300073470

Enrollment

Unknown

Registered

2023-07-12

Start date

2021-11-10

Completion date

Unknown

Last updated

2023-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

alcohol addiction

Interventions

No arousal/No sleep deprivation group:Normal sleep

Arousal/No sleep deprivation group:Alcohol related images+Normal sleep

No arousal/Immediate sleep deprivation group:Immediate sleep deprivation

Arousal/Immediate sleep deprivation group:Alcohol related images+Immediate sleep deprivation

No arousal /Sleep deprivation after 6 hours group:Sleep deprivation after 6 hours

Arousal /Sleep deprivation after 6 hours group:Alcohol related images+Sleep deprivation after 6 hours

Eligibility

Sex/Gender

Male

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: ? It met the Diagnostic criteria for alcohol use disorder in the Diagnostic and Statistical Manual of Mental Disorder ? (DSM-?); ? The Alcohol Withdrawal Scale (AWS) score was less than 5 after stopping drinking alcoholic beverages for at least 2 weeks; 3. Men; ? Age 18-50 years old; ? junior high school or above; ? No history of abuse of other psychoactive substances (other than tobacco); ?right-handed

Exclusion criteria

Exclusion criteria: ? Patients with severe neurological and mental diseases, cardiovascular diseases, liver, kidney and other organic diseases; ? Patients with brain trauma and other EEG contraindications; ? Patients with pacemakers, nerve stimulators, artificial metal heart valves, etc.; With aneurysm clips (except non-paramagnetic, such as titanium alloy); There are metal foreign bodies in the eye, inner ear implantation, metal prosthesis, metal prosthesis, metal joint, ferromagnetic foreign bodies in the body; Patients with unremovable metal foreign bodies (metal implants, dentures), insulin pumps, etc.; Patients with claustrophobic MRI contraindications; ? unqualified related learning.

Design outcomes

Secondary

Measure	Time frame
electroencephalo-graph;	—

Primary

Measure	Time frame
Blood Pressure and Heart rate;Craving level (VAS);	—

Countries

China

Contacts

Public Contacthan wang

The Second Affiliated Hospital of Xinxiang Medical College

799164828@qq.com+86 152 2618 0349

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026