Infertility
Conditions
Interventions
Experimental group:All patients were treated with an antagonist fixation protocol for controlled ovarian hyperstimulation,three months before the ovulation cycle, PEG-rhGH 3 mg/d subcutaneous injectio
control group:All patients were treated with an antagonist fixation protocol for controlled ovarian hyperstimulation without PEG-rhGH treatment.
Sponsors
Chongqing Health Center for Women and Children
Eligibility
Sex/Gender
Female
Age
38 Years to 42 Years
Inclusion criteria
Inclusion criteria: 1. Prepare for ICSI treatment; 2. Married women aged 38-42 (excluding 42); 3. 18 kg/m^2 <= BMI < 30 kg/m^2; 4. Previous ART cycles < 3 times (provide copies of previous cases); 5. Those who voluntarily participate and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Chromosome abnormalities (excluding polymorphism) in one or both spouses; 2. Male non obstructive azoospermia; 3. PCOS patients; 4. Patients who have used growth hormone within the past month; 5. Patients who have growth hormone Contraindication; 6. Individuals who are allergic to experimental drugs and excipients; 7. Researchers believe that individuals are not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oocyte Aneuploidy rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gn usage days;Gn usage;HCG day endometrial thickness;Number of retrieved oocytes;MII oocyte count;Fertilization rate;Number of D3 transferable embryos;Number of D3 high-quality embryos;Blastocyst formation rate;Serum IGF-1 level; | — |
Countries
China
Contacts
Public ContactLuo Yunyao
Chongqing Health Center for Women and Children
Outcome results
None listed