Alzheimer’s disease, Mild Cognitive Impairment, Subjective Cognitive Decline
Conditions
Interventions
Socially isolated SCD population:Observational research
Sponsors
Jiangsu Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
45 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1) Self-perceived continuous cognitive decline compared with the previous normal state, and is not related to acute events; 2) After adjustment for age, gender, and years of education, the standard cognitive test is normal, or the diagnostic criteria for MCI are not met. 3) Selected candidates can sign the informed consent form themselves.
Exclusion criteria
Exclusion criteria: 1) Age 85 years old; 2) Patients with vascular dementia or other organic brain diseases; 3) Modified Hachinski Ischemia Scale score > 4; 4) Those with blindness, deafness, severe speech disorders, etc. who cannot cooperate with cognitive function examination; 5) Those who have a history of drug or alcohol dependence and other substances within the past 6 months; 6) Participating in other cognitive-related clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of MCI and AD; | — |
Secondary
| Measure | Time frame |
|---|---|
| Auditory Verbal Learning Test Huashan Version,AVLT-H;Montreal Cognitive Assessment,MoCA;Wechsler Memory Scale-Revised Logical Memory,WMS-RLM;Wechsler Digit Span,WDS;Verbal Fluency Test,VFT;Boston Naming Test,BNT;Lubben Social Network Scale-6,LSNS-6;UCLA;Geriatric Depression Scale,GDS;ISI;PSQI;International Physical Activity Questionnaire,IPAQ;DTC;fMRI; | — |
Countries
China
Contacts
Public ContactZhuYi
Jiangsu Provincial People's Hospital
Outcome results
None listed